ee-reh-neh.bsky.social
Group leader in Human Genomics and Evolution at SVI in Melbourne, Australia. Durian evangelist. Sometimes I go to Estonia.
👤 Joined on 17 May 2023
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Very happy to be presenting a platform talk at #ASHG this week entitled: "Genetic negative control reveals confounders and disease subtypes in drug trial emulations" Room 520ABDE/Level 5 at 2pm. add it to your planner and I hope to see you there! ashg.floq.live/event/ashg-2...
Show PostDecoding super-enhancer regulatory grammar and pathogenic gain-of-function variants directly from DNA sequence https://www.biorxiv.org/content/10.64898/2026.10.11.756618v1
Show PostSystematic mapping of enhancers, silencers, and topological elements using prime editing deletion screens www.biorxiv.org/content/10.6... Check out our preprint on next-generation tech for mapping distal regulatory effects! We’re excited to help set this up - please get in touch Thread 👇
Show PostMeanwhile, at every home office in the world
Show PostAre weak TF motifs important? Weilert et al use deep learning to systematically map low-affinity pioneer binding sites in mESCs and show that they cooperate with strong pioneer motifs to drive chromatin opening. Paper: www.cell.com/cell-genomic... Preview w/ Grace Bower: www.cell.com/cell-genomic...
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