davidjonesbrain.bsky.social
Behavioral neurologist and AI director working to end degeneration of mental function and use technology to transform the practice of neurology. Neuro AI Program (NAIP) https://naip.mayo.edu https://www.youtube.com/channel/UCj9q9jnuNZNNZnx48-P1vkg
👤 Joined on 06 December 2023
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@davidjonesbrain.bsky.socialExciting update! You can run Image Based Meta-Analyses (IBMA) on our platform 🚀 We've known for ~TWO decades that images are better than coordinates, but data has never been shared/organized properly to make that an accessible reality. We did it, enjoy: compose.neurosynth.org
Show PostReally excited about this work with the awesome Will de Cothi & @shipleysj.bsky.social, out in Nature Reviews Neuroscience. We propose acetylcholine is an analogue of dopamine — tracking not reward prediction errors but state-transition prediction errors. https://doi.org/10.1038/s41583-026-01058-w
Show Post🧠 New paper out in 𝘉𝘳𝘢𝘪𝘯 Why does tau pathology often begin in the entorhinal cortex in Alzheimer’s disease? We show that brain-wide gradients of neuronal activity and amyloid-β may make this region particularly vulnerable to tau pathology. academic.oup.com/brain/articl...
Show PostNew results! The prefrontal cortex uses a compact, low-dimensional “coding space”. Information can be captured in just 3–6 dimensions. The brain compresses what we remember. Low-dimensional prefrontal representations of objects during working memory doi.org/10.64898/202... #neuroscience
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