Veronica Finazzi

Veronica Finazzi

veronicafin.bsky.social

EpiCrossBorders PhD student (Scialdone lab @ Helmholtz Munich and Vallejos lab @ IGC, Edinburgh) Exploring transposable element activity in single-cell omic datasets

👤 Joined on 17 February 2024

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  • 17 Şub 2024, 16:31
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @veronicafin.bsky.social

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❤️ Beğendiği Gönderiler

🚨New preprint🚨, sharpening our characterisation of regulatory changes and human brain evolution. Thanks to new FANTOM6 data, we now focus on noncoding RNAs and how ncRNA–TF cooperation + selective cis-regulatory rewiring could have contributed to sapiens-specific aspects of cortical development 🧪🧠🧬

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Kudos to Marlene and Veronica who lead the experimental and computational part, and @alessandrovitriolo.bsky.social and Giuseppe with whom we shared the supervision! Special thanks to the families of individuals affected by Gabriele de-Vries syndrome who provided samples to generate #iPSCs

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I'm proud to share that our modeling of #YY1 haploinsufficiency has just been published! www.nature.com/articles/s41... Using #organoids and #neurons we discovered that YY1 mutations affect the cross-talk between cells and also cause a non-cell autonomous phenotype in a cell-type specific manner.

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