@biorxivpreprint.bsky.social Persistently activated virus-specific CD8 T cells indicate antigen-driven immune aberrations in long COVID www.biorxiv.org/content/10.6... @ejohnwherry.bsky.social @upenn.edu @markmpainter.bsky.social

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Human lung organoid modelling of tissue-resident antiviral T cell responses @nature.com @stanfordmedicine.bsky.social www.nature.com/articles/s41...

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@biorxivpreprint.bsky.social A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity www.biorxiv.org/content/10.6...

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Our paper is out! It turns out that finding the right TCR partner is a bit like matching socks🧦: almost every pair fits, but only a small fraction make the right match for antigen recognition. If you don’t feel like diving into the full paper, there’s also a one-page summary!

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TCR specificity prediction is advancing rapidly. The central question is not only which TCR sequence recognizes an antigen, but also which TCR pairings make recognition possible & where is the binding boundary? Our new paper tackles these questions. 🧵 www.science.org/doi/10.1126/...

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