Great question, we have not looked. We could do that in the Ptf1a/IslcKO mice; they survive for a few months, but they do lack pancreatic islets (didn't really think about off-target effects when we generated the mice!!). The ChAT/Isl1 mice die by P12 because of motor neuron defects.

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Thrilled to have the latest work from the lab live on BioRxiv! This is @yessicasantana.bsky.social dissertation work, examining the role that the transcription factor Isl1 plays in starburst amacrine cell development. www.biorxiv.org/content/10.6... A brief explainer.... 1/10

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Hey, #ISER2026 peeps: I've finally got the snapshots of the meeting up. Some of ya'll are in there: bryanwjones.com/2026/08/iser...

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Again, you can’t go to any vision research conference, anywhere in the world without seeing @webvision.bsky.social content. This one is at the Helsinki Vision conference.

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New preprint! Another piece from @gaparicio.bsky.social thesis, now exploring the role of PALS1 (aka Nok, or MPP5) in lamination and photoreceptor progenitors positioning in the developing zebrafish retina and retinal organoids: tinyurl.com/yya754tf

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