Maini Lab @IIT UCL

Maini Lab @IIT UCL

mainilab.bsky.social

A friendly immunology lab, focused on harnessing adaptive immunity in tissues for optimal frontline defence against hepatitis B, liver cancer and coronaviruses.

👤 Joined on 19 November 2024

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  • 19 Kas 2024, 23:11
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @mainilab.bsky.social

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❤️ Beğendiği Gönderiler

We're delighted to see immunologists once again recognised by the #NobelPrize! 🏆 Warm congratulations to the winners - their contributions have been vital in shaping our understanding of the immune system. More here: www.immunology.org/news/british...

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Our paper is out! Check out this beautiful story where we uncovered that the costimulatory molecule ICOS is detrimental for PD-1+ CD8 T cells. Sustained ICOS signaling reduces memory-like features of progenitor exhausted CD8 T cells in chronic viral infection and liver cancer.

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Antigen-specific antibodies secreted by plasma cells are rapidly identified using microfluidics and fluorescence-activated cell sorting (FACS) go.nature.com/4dHLaHB rdcu.be/etg8W

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1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)

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Well done to Brittney Prusty, Stuart Flanagan & all the clinical research team for work on small volume blood testing for #HIV, aiming to reduce barriers to monitoring. Poster highly commended! 🥇 More to follow on this project, watch this space. @cnwlnhs.bsky.social #BHIVA25 @bhiva.bsky.social 🧪

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