Alexis Verger 🧬🧫🧪

alexis-verger.cpesr.fr

07 April 2025 10:07

BoltzDesign1: Inverting All-Atom Structure Prediction Model for Generalized Biomolecular Binder Design by @yehlincho.bsky.social @martinpacesa.bsky.social @sokrypton.org 🧶🧬 www.biorxiv.org/content/10.1...

Martin Pacesa

martinpacesa.bsky.social

11 December 2024 00:31

We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders! www.biorxiv.org/content/10.1...

Sonja Welsch

sonjawelsch.bsky.social

01 December 2024 09:41

I really wonder what tools we will end up using to study functionality of all these mini proteins? In my naive view, #fluorescent tagging/imaging and #cryoEM won’t be viable options? 🧬🧪

Martin Pacesa

martinpacesa.bsky.social

13 November 2024 00:31

v1.2.0 of BindCraft released on github. Includes improvements to the Colab notebook, new design protocol options, several critical bug fixes in the run script, QoL improvements, and streamlining of the installation script. github.com/martinpacesa...

jess m. ☕🍂

jametc.bsky.social

29 February 2024 09:19

TIL learned a fun fact the vast, vast majority of microplastics aren't actually from breaking down single-use plastics like I thought, but from car tires. Car tires, simply by being worn down while driving, emit more microplastics than anything by far