wildtypemc.bsky.social
Microbiome gen(om|et)ics, secondary metabolism, comp bio, antibiotic/drug disco, evolution, & hockey. he/him.
👤 Joined on 30 July 2023
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@wildtypemc.bsky.socialSave the date! Our final talk of the Productive Failure Series! 'When Antibiotics Fail', March 18th, 7pm, Discovery Building De Luca Forum. @wildtypemc.bsky.social Marc Chevrette and Tiny Earth's Sarah Miller discuss lifesaving drugs: how they are discovered & what we can do to keep them potent.
Show PostNow out in @acs.org JACS Au, the manuscript by #BarbaraTerlouw et al. describing PARAS, a high-accuracy machine-learning algorithm to predict substrate specificities of nonribosomal peptide synthetase (NRPS) adenylation domains, key for estimating natural product structures from BGC sequence. 1/n
Show PostThanks to great collaborations with #GregChallis, @wildtypemc.bsky.social , @gillesvanwezel.bsky.social #SerinaRobinson #MattJenner #FabrizioAlberti and many others.
Show PostSee a brief review summarizing the use of synthetic microbial communities (SynComs) for revealing the ecology of specialized metabolites [my holiday break writing exercise] portlandpress.com/essaysbioche... #MicrobiomeEcology at Institute of Biology Leiden (IBL)
Show PostThe review is heavily based on the publications of @wildtypemc.bsky.social (2023 PNAS), Morten Lindqvist Hansen (2022 ISME J and 2024 ISME J), @neftalyl.bsky.social (2023 ISME Commun and 2025 ISME J), Heiko Kiesewalter (2020 Beilstein J Org Chem), Augustin Rigolet (2024 Microbiol Spectr) [2/3]
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