This in @nature.com makes great points on how to enhance scientific creativity. In the UK, core-funded institutes have been very successful in this. The long-term funding allows much higher risk taking and reduced administrative burdens protect time for deep work. www.nature.com/articles/s41...

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Added something to chimerax-trimmings that I have wanted for ages! Added old Chimera-style model controls, so that one can freeze or activate specific models and freely rotate/translate them with respect to one another. Implemented as modelmotion in latest version. github.com/olibclarke/c...

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📢 Calling all prospective PhD students! Why not consider the LMB for your PhD? 🎓🧑‍🔬 Applications are now open to join us in October 2027. Explore what’s on offer here: https://mrclmb.ac.uk/careers-and-people/phd-students/research-projects/

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1/1 How does a single methyl group activate bacterial defence? In my PhD work with @matthiaswilmanns.bsky.social and @typaslab.bsky.social, we reveal how this tiny DNA modification triggers retron disassembly and toxin activation. Now on bioRxiv: www.biorxiv.org/content/10.6...

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3/11 Our cryo-EM structure reveals RcaT encased as an inactive dimer within a four-component core retron complex that can further assemble into filaments.

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