It’s a reminder that even some of the people doing very visible and important work in the field still don’t have a firm handle on PEM.

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This is a review by a good group doing good work but tries to do too much, and in the process, makes some pretty basic mistakes.

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“Currently, diagnosis of PEM is strictly clinical, wherein patients must fulfill criteria for the DePaul Symptom Questionnaire – Post-Exertional Malaise (DSQ-PEM) questionnaire [39].” Incorrect. Strictly clinical? Sure. DSQ-PEM is used to make the diagnosis? Nope. www.cell.com/trends/endoc...

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Keep your face always toward the sunshine and shadows will fall behind you. Walt Whitman As always

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Everyone with PEM/PENE has dysautonomia but not everyone with dysautonomia may have PEM/PENE. Pass it on.

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