avbroeck.bsky.social
Assistant Prof. @universitedeliege.bsky.social @frsFNRS @erc.europa.eu | Postdoc @rockefelleruniv.bsky.social | PhD @igbmc.bsky.social @unistra.fr | Studying RNA-protein machines ⚙️🏗 using cryo-EM ❄🔬
👤 Joined on 29 March 2025
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@avbroeck.bsky.socialHappy to share that, after 17 years abroad, I’m returning to Poland to establish my lab at IIMCB in Warsaw! 🇵🇱 Excited to start this new chapter and looking forward to the adventures ahead!
Show PostI’m very excited to share my postdoc work in the @plaschkalab.bsky.social, where we investigated the very final act of splicing – spliceosome termination, revealing the stepwise dismantling of the spent spliceosome www.nature.com/articles/s41... (1/11)
Show PostAfter excising an intron, the spliceosome gets trapped on the branched intron-lariat RNA. How are such dead-end spliceosomes terminated? Our latest paper led by @vytaute.bsky.social investigates the mechanism of spliceosome termination www.nature.com/articles/s41... (1/6)
Show PostNew preprint from Dodonova lab 🔔! Capturing multiple states by cryo-EM❄️, we show for the first time how archaeal RNA Polymerase engages a nucleosome and forms direct contacts with histones! 🧬 Great work by Gabriele & a fantastic collaboration with Dina Grohmann! 🧵 www.biorxiv.org/content/10.6...
Show PostNew from the lab! We uncover how the cap-binding complex promotes first-intron splicing: ZC3H18 recruits splicing factors while competing with the RNA-decay machinery, linking two alternative fates for newly made RNA. doi.org/10.1016/j.mo...
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