dr-dparker.bsky.social
Postdoc at Karolinska Institutet in Andrea Fossati's lab studying phage-based antimicrobials with proteomics and functional genomics
👤 Joined on 24 September 2023
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@drrparker.bsky.social@drrparker.bsky.social → @drdrparker.bsky.social@drdrparker.bsky.social → @dr-dparker.bsky.socialWhat does it take for a mycobacteriophage to infect M. smegmatis mc² 155? 🦠🗺️ We mapped it for 70 phages using genome-wide CRISPRi. Our new preprint from the Phage Foundry is out! (phagefoundry.org) 🥳🧵 Read the preprint here: www.biorxiv.org/content/10.6...
Show PostA new preprint 🎉 from phagefoundry.org Mycobacteriophages are candidate therapies for drug-resistant mycobacterial infections, but we still don't know how most of them get into their hosts. Our new preprint tackles this challenge 👉🏽 www.biorxiv.org/content/10.6...
Show PostHow bacterial immune systems sense phage infection #bacteriophage #phage #microSky #scienceSky www.nature.com/articles/s41...
Show PostI'm happy to share one of my favorite projects from the past 4 years. 'Piercing mechanism in the minimal contractile tail of bacteriophage P2'. In this preprint, we applied #cryo-EM, #cryo-ET, TEM, and #computationalbiology to study the #phage P2 virion structure and its contraction mechanism.
Show PostSo happy to share that this work is finally out, now in @nature.com! Lots of new goodies since preprint so plz check it out (old thread below). Giant thank you to everybody involved + all @savitski-lab.bsky.social and @typaslab.bsky.social lab members 🙏🙏🙏 @embl.org nature.com/articles/s41...
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