Systematic mapping of enhancers, silencers, and topological elements using prime editing deletion screens www.biorxiv.org/content/10.6... Check out our preprint on next-generation tech for mapping distal regulatory effects! We’re excited to help set this up - please get in touch Thread 👇

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Thank you for the thoughtful summary and perspective!

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Today in Nature @nature.com, we report a new approach to studying human brain development and modeling disease in vivo. Open article link below 👇

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A paper in Nature presents the largest-known map of gene expression in the human prefrontal cortex region of the brain. go.nature.com/46BFtJZ 🧬🧪

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I'm thrilled to share the published version of our paper, now officially out in Neuron! Read it here: authors.elsevier.com/c/1no8J3BtfH... One updated highlight: with new analyses we now show how functionally-defined groups of neurons putatively overlap with molecular cell types in LPBN

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