Surprisingly, histones have also been characterized in bacteria, including a bacterium found in soil and aquatic environments and in a spiral-shaped gram-negative bacterium More at Molecule of the Month: pdb101.rcsb.org/motm...

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Sophie Polo has been awarded an Impulscience grant from the Bettencourt Schueller Foundation to fund a research project on the establishment and maintenance of the inactive X chromosome in response to DNA breaks. This is wonderful news for the lab! We thank the Foundation for their support.

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A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of #DNA coiled around a core of histones. Explore the x-ray crystallography data and #3Dprint the #Nucleosome COMPASS Complex. #genetics #biotech #CRISP https://buff.ly/3Xo6Dx3 @caseysteffen

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📢 New preprint: Experiment-guided AlphaFold3 resolves accurate protein ensembles. doi.org/10.1101/2025... AlphaFold3 is incredible, but has crucial limitations: it typically collapses to a single conformation, ignoring the inherent dynamics of proteins. And it can be wrong. Here's a solution. 🧵👇

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Kapalı içerik

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