UCSF Broad Stem Cell Center

ucsfstemcell.bsky.social

26 August 2026 19:35

@robertblelloch.bsky.social + team engineered iPSC-derived dendritic cells coated w/ patient tumor membranes to present multiple cancer antigens to T cells. The approach induced tumor-specific T cell responses in patient samples and slowed tumor growth in humanized mice. www.cell.com/cell-stem-ce...

Deniz Gökbuget

denizgoekbuget.bsky.social

26 August 2026 19:31

Excited to share this new paper: Universal iPSC-derived dendritic cells "dressed" with tumor MHC complexes as an off-the-shelf cancer vaccine. Glad I could help on the computational side. Congrats to @huaigengxu.bsky.social, Chisato, @robertblelloch.bsky.social for getting this over the finish line!

HuaigengXu

huaigengxu.bsky.social

11 June 2025 03:40

Dress to kill. Come to see how I created a novel cancer vaccine by transferring MHC-peptide complexes from tumor cells to universal iPSC-derived Dendritic cells. #ISSCR2025 AI and Cancer Evolution Session, Friday 8:30am, Convention Hall B, level 1 @ucsfcancer.bsky.social @ucsfstemcell.bsky.social

Deniz Gökbuget

denizgoekbuget.bsky.social

06 February 2025 21:46

🚨 New Paper Alert! 🚨 Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️