Micro- and nanoplastics enter our bodies through food and water. But what happens once they pass through the gut barrier? In our new study in Nature Metabolism, we show that #Kupffer #cells, the resident #macrophages of the liver, are the main reservoir for ingested plastic.

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More than thrilled to share that I’ve been promoted to full (tenured) Professor @harvardmed.bsky.social @harvard.edu! This only happened because of the hard work of many people, but I want to dedicate this promotion to my grandmas, Nonna Maria & Nonna Vevè. A #FirstGen thread 🧵 1/x

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Great fun to write this review on Kupffer cells with Florent Ginhoux and Paul Kubes, covering origin, diversity and roles in immunity and metabolism, now out in @natrevimmunol.nature.com. Huge credit to Bruna Araujo David, Francesco Andreata and Camille Blériot for driving this work. t.co/rGpmTMRddV

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Issue 2 is complete! On the cover: Electron micrograph depicting a neonatal hepatocyte densely filled with glycogen (yellow). Nuclei (purple) and mitochondria (red) pseudo-coloured as well. See the Research Article by Nikola Makdissi et al. from @masslab.bsky.social lab: doi.org/10.1242/dev....

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New review from the @becherlab.bsky.social about the role of IL-12 and IL-23!

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