Structural Biology

actacrystd.iucr.org

29 November 2025 01:30

Giles and Burnley: Ten years of the CCP-EM Spring Symposium #Cryoem #ElectronCryoMicroscopy #CCPEM ... #IUCr https://journals.iucr.org/paper?S2059798325010496

jake

mediocre-jake.bsky.social

20 November 2025 19:07

Sir Philip Cohen presenting on the intersection between glycogen metabolism and ubiquitination From insulin signaling to glycogen Really appreciate the historical tour of ubiquitin in innate immunity @ausub.bsky.social #ubiquitin #AusUb2025 #LorneUbiquitin2025

Stephan Hacker

stephanhacker2.bsky.social

19 November 2025 20:46

Exciting @biorxivpreprint.bsky.social by the groups of @pjcossar.bsky.social and @alessiociulli.bsky.social. They use a molecular glue between 14-3-3 and an intrinsically disordered domain of ERα to develop a molecular glue-based PROTAC recruiting VHL. doi.org/10.1101/2025... #TPD #ChemSky #ChemBio

cryoEM papers

cryoempapers.bsky.social

19 November 2025 20:45

Induced ubiquitination of the partially disordered Estrogen Receptor alpha protein via a 14-3-3-directed molecular glue-based PROTAC design www.biorxiv.org/content/10.1101/2025.11.17.688825v1 #cryoEM

MRC Laboratory of Molecular Biology

mrclmb.ac.uk

22 October 2025 22:51

Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing Read more: www2.mrc-lmb.cam.ac.uk/a-new-method... #LMBResearch