agnelsfeir.bsky.social
Scientist. https://www.sfeirlab.com/ Prof. at MSKCC and co-founder of Repare Therapeutics. 🇱🇧+🇺🇸 in NYC
👤 Joined on 27 November 2023
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@agnelsfeir.bsky.socialHappy to share our collaborative project with Stephane Marcand, on the protective role of Rap1 at telomeres. It turned out that our favorite protein, MRX, has the ability to measure telomere length, and activate response pathways when telomeres become too short. www.nature.com/articles/s41...
Show PostExciting opportunity to work with an amazing scientist at the cutting edge of DNA repair and telomere biology.
Show PostNew lab preprint! ERCC6L2 disease is a recessive bone marrow failure syndrome caused by mutations in the putative DNA helicase ERCC6L2. Using mouse genetics, biochemistry and AF3 we uncover ERCC6L2-MRI as a KU-regulatory complex stimulating NHEJ at staggered DSBs: www.biorxiv.org/content/10.1...
Show PostVery grateful to the Danish Cancer Society and our MBG colleagues for their support! This grant will enable us to expand our research scope and grow our team. mbg.au.dk/en/news-and-...
Show PostMeet #MSKPostdoc Megan E. Kelley (@meganekelley.bsky.social) in the @agnelsfeir.bsky.social Lab, where she studies error-prone DNA 🧬 damage repair in the context of cancer and drug resistance. 👏 Congrats to Megan on receiving both the NCI F32 and MSK Society Scholar awards! #NPAW2025
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