dr-l-mcculloch.bsky.social
Principal investigator at the University of Edinburgh. Research on the systemic immune response to stroke and complications of stroke recovery. #Bcells #infection #GIdysfunction #cognitivedecline Wellcome Sir Henry Dale fellow
👤 Joined on 20 February 2025
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@dr-l-mcculloch.bsky.social'Analysis of surviving DTCs revealed glucocorticoid receptor activation as a key driver of resistance to both CD8+ T cells & natural killer cells. Niche profiling using an optimized labelling tool identified FAS–FASL as a key pan-cytotoxic pathway against DTCs, which is repressed by GR activation'
Show PostThe cribriform plate: A dynamic central nervous system immune hub. Review from Collin J. Laaker, Zsuzsanna Fabry and colleagues: rupress.org/jem/article/... 📘 In our #Lymphatics collection: rupress.org/jem/collecti...
Show PostGreenlandic politician and former MP Tillie Martinussen: “We do not want to be rich like [USians]. Look how greedy they are, even trying to invade their friends. We would not sell ourselves.”
Show PostTwo new papers from the McCulloch lab reveal how the body changes after experiencing a stroke. 1. Stroke and “fight-or-flight” response weakens the immune system > edin.ac/4a166dD 2. Long term changes to the intestinal microbiome seen after stroke > edin.ac/4jR2LBl
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