Astbury Biostructure Laboratory

Astbury Biostructure Laboratory

astbury-bsl.bsky.social

#CryoEM #CryoET @universityofleeds.bsky.social Funded access via @instruct-eric.bsky.social Find out more about our training: http://bit.ly/3Szodyw

👤 Joined on 15 January 2025

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  • 15 Oca 2025, 12:47
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @astbury-bsl.bsky.social

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Great to be at the @eptri.bsky.social Scientific Meeting 2026 in Warsaw this week! Meet us for talks from Director Prof. Harald Schwalbe (@schwalbe-lab.bsky.social) on interactions with EPTRI, plus great contributions from Jan Pribyl of @ceitec.eu and Oksana Degtjarik of @astbury-bsl.bsky.social!

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What you're looking at is one of the reasons pineapple hurts to eat. These needle-like crystals of calcium oxalate are called 'raphides' & they're designed to puncture your mouth & throat while digestive enzymes (papain & bromelain) break down your tissues. Pineapples are trying to eat *US*.

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I described our internships but it is best to hear from one of our interns how much it has helped! From @astbury-bsl.bsky.social to @embl.org Heidelberg, thank you @simonemattei.bsky.social for sharing your expertise with Instruct interns By the way call now open! instruct-eric.org/submit-call/...

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Seg-3 interacts with the RLC “latch”, which lies close but remains flexible. Phosphorylation of S19 here is predicted to disrupt this interaction through steric clash and charge repulsion, releasing the latch from its shutdown position. (4/11)

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We identify the RLC “mortar”, where the Free Head RLC N-terminus stabilises the interface between the heads. The phosphorylation site S19 is exposed and accessible, suggesting phosphorylation disrupts this interaction. (3/11)

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