New preprint: Revisiting the methodological foundation of lesion network mapping. doi.org/10.64898/202... A thread.

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Delighted to share our new paper on schizophrenia-related stigma. We argue that explanatory models grounded in predictive processing may offer advantages over classical neurobiological illness models in understanding psychosis — and may even help reduce stigma. www.nature.com/articles/s41...

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We further present a framework integrating the different evidence and propose a path forward for future biomarker research: www.nature.com/articles/s41...

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Despite decades of research there are still no reliable biomarkers for any of the major psychiatric diagnoses. In this now published perspective in Molecular Psychiatry we consolidate evidence from genetics, exposome and neuroimaging research on the potential reasons underlying these failures.

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This study examined how comorbid anxiety alters structural brain connectivity in major depressive disorder, with findings that challenge the dysconnection hypothesis in anxious depression & support symptom-based neuroimaging approaches 🧠

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