cusbg.bsky.social
Research group at the intersection of structural bioinformatics 🧬 and machine learning 🤖. Developing http://prankweb.cz, http://apoholo.cz, https://rnacentral.org/r2dt Lab: bioinformatics.cuni.cz/cusbg Heads: @davhox.bsky.social & @majek.bsky.social
👤 Joined on 16 November 2024
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@cusbg.bsky.socialWe have a little new paper at ICLR led by @AntonBushuiev. Test time training for proteins :) arxiv.org/abs/2411.02109 For example, you know the sequence that you want to fold, so fine-tune ESM on it at test time to get a better ESMFold structure prediction!
Show PostWe train machine learning models on millions of proteins. But when it comes to making predictions, do we need them to understand all proteins at once? Often, we need an accurate model for the specific protein we are studying or designing. We address this with ProteinTTT arxiv.org/abs/2411.02109 1/🧵
Show PostVery happy @roman-bushuiev.bsky.social and I joined the amazing team led by @hannes-stark.bsky.social to work on BoltzGen, a generative model for binder design based on Boltz-2. Excited what it will enable!
Show PostProteinTTT is now easy to run on Hugging Face Spaces and Google Colab. We’ll also be presenting the paper at ICLR 2026 🇧🇷 🤗 Hugging Face Space: huggingface.co/spaces/pimen... ⚙️ Google Colab: colab.research.google.com/drive/1l_h7c... 🧵👇
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