degiovannilab.bsky.social

👤 Joined on 02 December 2025

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  • 02 Ara 2025, 09:12
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @degiovannilab.bsky.social

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Interesting link between aging, serotonin, platelets and COVID-19 severity. A new study in Science Immunology from @iannaconelab.bsky.social and colleagues identifies platelet-derived serotonin as a driver of age-related lung pathology following SARS-CoV-2 infection. www.science.org/doi/10.1126/...

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Science Magazine
02 September 2026 09:07

Platelet-derived serotonin drives excessive clot formation in the lungs and promotes severe respiratory disease during SARS-CoV-2 infections in aging mice. Learn more in #ScienceImmunology: https://scim.ag/4gntJAp

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Thanks for sharing!

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In aging hosts, platelet serotonin fuels lung-damaging clots, leading to enhanced respiratory distress in the context of COVID-19 @sciimmunology.bsky.social www.science.org/doi/10.1126/... @iannaconelab.bsky.social @davidemarotta.bsky.social

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Blocking serotonin uptake or 5-HT2A protects, with no cost to viral control. Kudos to postdoc Davide Marotta, who spearheaded the work, and to Marco De Giovanni for co-supervising it - a very fun collaboration between our two labs. 2/2

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