degiovannilab.bsky.social
👤 Joined on 02 December 2025
Followers
Following
Total Posts
@degiovannilab.bsky.socialInteresting link between aging, serotonin, platelets and COVID-19 severity. A new study in Science Immunology from @iannaconelab.bsky.social and colleagues identifies platelet-derived serotonin as a driver of age-related lung pathology following SARS-CoV-2 infection. www.science.org/doi/10.1126/...
Show PostPlatelet-derived serotonin drives excessive clot formation in the lungs and promotes severe respiratory disease during SARS-CoV-2 infections in aging mice. Learn more in #ScienceImmunology: https://scim.ag/4gntJAp
Show PostIn aging hosts, platelet serotonin fuels lung-damaging clots, leading to enhanced respiratory distress in the context of COVID-19 @sciimmunology.bsky.social www.science.org/doi/10.1126/... @iannaconelab.bsky.social @davidemarotta.bsky.social
Show PostBlocking serotonin uptake or 5-HT2A protects, with no cost to viral control. Kudos to postdoc Davide Marotta, who spearheaded the work, and to Marco De Giovanni for co-supervising it - a very fun collaboration between our two labs. 2/2
Show Post