eecutts.bsky.social
Interdisciplinary biochemist/structural biologist. Works with SMC complexes and their friends. Here for science.
👤 Joined on 08 October 2023
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@eecutts.bsky.socialPrecise DNA base editing using AlphaFold3-based contact modelling www.nature.com/articles/s41... www.nature.com/articles/d41...
Show PostHow does an embryo generate the right cells in the right place? Delighted to share our latest findings on how neural crest cells acquire vagal or trunk identities Spoiler alert: The timing & combination of CDXs preconfigures cell identity & distinct HOX states www.biorxiv.org/content/10.6...
Show PostESCRTs are repurposed when missegregated DNA persist during nuclear envelope reformation, at this point ESCRT-III binds this DNA and mounts the NoCut response to protect the genome
Show PostHouse moves always start feeling very real when solicitors ask for large sums of money!
Show PostOur latest paper is out! 🎉 We show that the HSV-1 origin binding protein UL9 tethers dsDNA thereby forming intramolecular DNA loops and intermolecular DNA tethers. 🤝 www.nature.com/articles/s41...
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