Our lab is obsessed by hidden biology - protein products central to understanding how our cells function, but missing from standard genome annotations. Introducing new work from post-doc Eric Smith on alternative translational isoforms for heterochromatin protein 1. www.biorxiv.org/content/10.6...

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As our latest research manuscript spends its 114th day in peer review, while two of my grants await study section in the next two weeks, and I agree to review my 17th manuscript of 2026, on top of having managed 9 manuscripts as an academic editor this year, my belief in karma falls to a new low

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Very happy to see our work highlighted by @natcellbio.nature.com. A great team effort and a fascinating example of how a simple physical principle can connect mitosis across eukaryotes! @lgudlin.bsky.social, @krunovuk.bsky.social, @kopslab.bsky.social

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🚨🚨Preprint alert!🚨🚨 We removed the main centromere 3 domain of Drosophila‼️ We designed an inducible dCas9-Fok1 system to cut 🧬 at unique sequences flanking the ~50-kb island where most of CENP-A sits. To our knowledge, this has never been attempted in a living animal!

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Excited for this new chapter!

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