Jan-Hannes Schaefer

Jan-Hannes Schaefer

jhschaef.bsky.social

Structural Biology to the rescue. Postdoc at Scripps Research. https://jhschaefer.de/ ❄️🔬 🎹⛳

👤 Joined on 14 November 2024

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  • 14 Kas 2024, 15:15
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @jhschaef.bsky.social

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Struggling to choose a pixel size for your cryo-ET acquisition? Worry not: super-resolution processing can take in situ subtomogram averaging beyond physical Nyquist! We reached 2.8 A loc-res of a ribosome dataset with 4.78 A physical Nyquist limit! Our new preprint 👇: doi.org/10.64898/202...

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Oli Clarke
18 October 2026 23:16

Added something to chimerax-trimmings that I have wanted for ages! Added old Chimera-style model controls, so that one can freeze or activate specific models and freely rotate/translate them with respect to one another. Implemented as modelmotion in latest version. github.com/olibclarke/c...

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15 October 2026 01:58

1/5 Cryo-EM gives high-resolution RNA structures, but only when high Mg²⁺ freezes out their motion. At physiological conditions, RNAs are dynamic and 3D reconstruction fails. Can we still learn their folding equilibria? New preprint: yes, straight from the raw particle images👇

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James Fraser
11 October 2026 01:40

I hear so much about the growing power of predictive biology, especially in drug discovery and "co-folding". I want to see people put their GPU budget where their mouth is!

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Congrats Jan!

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