I mean look at this video!

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🚨New preprint! Ligands at the same GPCR can produce wildly different signaling outputs. Why? We built a mutational scanning platform to measure ~10,000 µOR variants across 15 opioids, yielding ~400k measurements of how sequence and ligand chemistry set signaling. www.biorxiv.org/content/10.6... 1/10

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Thank you to everyone sharing in this moment! I’m so grateful to all my trainees & collaborators… dlab.stanford.edu/group-members (pic: Peter and I together in 2017) Reading for all those asking: for technical details: dlab.stanford.edu for everyone: deisseroth.org/projections

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Congratulations to our first Nobel Prize laureate of 2026 🎉 Early this morning Karl Deisseroth found out he was awarded this year's Nobel Prize in Physiology or Medicine. He seems very happy with the news!

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I'm SO excited to have this out in the world!!!! Check out our latest work on the contribution of the anterior hypothalamic nucleus to stress sensitivity and valence processing.

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