gastropaul.bsky.social
Retired after 44 years of clinical practice but still addicted to GI. Lecturer. Literature nerd. Lakes, canoeing, kayaking are also happy places.
👤 Joined on 12 November 2024
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@gastropaul.bsky.socialProposal: for complex patients (eg ICU) we should *always* get CBC w/ differential (not a plain CBC) - Same amount of blood - Run by the same machine (it usually CHECKS the differential & just dumps the data!) - Trivial cost difference - Can be helpful (eg Eos 2/2 drug, NLR) #EMIMCC
Show Postwe’ve integrated the PREOXI trial into our practice so well that there’s an entire cabinet in our ICU dedicated to it 😁 this improves intubation success & safety. I’vd wanted to do this for a decade but the RCT provided EBM backing to push it forward more here emcrit.org/pulmcrit/bsi/
Show Postone fun thing about using phenobarbital for seizures in ICU is that you can be as precise as you want (PK is predictable & levels turnaround fast) high precision usually isn't needed but if the neuro team wants me to hit a specific phenobarbital level in brittle SE, I'm on it 🫡. #EMIMCC
Show Postmy key advice on bupropion XR intoxication: if you intubate a patient for seizures, place a gastric tube & start whole bowel irrigation immediately don't debate, just do it irrigation reduces ongoing drug absorption, minimizing deterioration more emcrit.org/ibcc/bupropi...
Show Posteveryone learns about TCA overdose in med school, but not bupropion XR overdose time to level up bupropion XR overdose is increasingly common & VERY dangerous ongoing drug absorption creates a "toxin bomb" wherein patients look OK initially, but deteriorate later on... (#1/2) #EMIMCC
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