klausenhauser.bsky.social
🇨🇦🇭🇰 @EPFL_en protein production + structure facility 🇨🇭| ex @ubc @uwaterloo @unige_en | here for #proteins #structuralbiology #xray #cryoem #plants #mountains #politics #transit #urbanism 🐱🐈 staying for the #hottakes | My views here🧪🧬🌱🔬🏳️🌈
👤 Joined on 09 September 2023
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@klausenhauser.bsky.socialLoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com
Show PostA Structure-Based hERG Pose Selection Workflow Integrating Induced-Fit Docking, Shape Similarity, Interaction Fingerprints, and Molecular Dynamics www.biorxiv.org/content/10.64898/2026.10.07.757389v1 #cryoEM
Show PostFor those who are not yet familiar with the tool: It analyzes your AF3 predictions of proteins with other proteins, DNA, RNA, or ligands. As output, it gives you an interface chord diagrams with a confidence score (piCS), plus summary tables of the predicted interfaces.
Show Postgenuinely where did they find her?
Show PostMy little electric Smart car next to an American pickup truck. Thinking that the whole Smart car would fit within the engine compartment of the GMC.
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