jennynathans.bsky.social
MD/PhD Univ Wash, PhD candidate in Jay Shendure lab | Yale '18 | NRSA Fellow | genomics, synth bio, & precision medicine 🧬 💫
👤 Joined on 21 September 2023
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@jennynathans.bsky.socialHere is the link for the paper www.biorxiv.org/content/10.6...
Show PostThrilled to share my freshly "baked" Baker lab paper. We took a bottom-up approach to designing transcriptional regulators. Instead of relying on natural activation domains, we designed compact proteins that recruit specific cofactors. Activators for now, repressors to come!
Show PostA map of normal development gives researchers a baseline for understanding birth defects, cancer, and more, revealing when and where cells go off course. The full tree is public via an interactive browser called NextCell: nextcell.seattlehub.org
Show PostUsing tech called DNA Typewriter, which writes genetic stamps into a cell’s genome every time it divides, the team was able to read 1.58 million cell nuclei to reconstruct the whole lineage. www.science.org/doi/10.1126/...
Show PostScientists at Seattle Hub for Synthetic Biology just built the largest cellular family tree ever for a mammal, tracing how a single egg divided into 1.28 million cells. bit.ly/4zqcRjh
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