bioRxiv Bioinfo

biorxiv-bioinfo.bsky.social

22 September 2026 19:10

DeepSCENIC: transfer learning from sequence-to-function models enables causal gene regulatory network inference https://www.biorxiv.org/content/10.64898/2026.09.18.752607v1

Cas Blaauw

casblaauw.eurosky.social

22 September 2026 19:06

Excited to show deepSCENIC to the world! GRNs meet sequence-to-function models: explicit TF-region and region-gene links, with the power of enhancer DL models, predicting RNA & ATAC at single-cell resolution. Check out the examples in the paper or try it on your own data: github.com/aertslab/Dee...

バイオステーション

bio-station.bsky.social

30 July 2026 13:25

転写が活発な遺伝子のブレーキ役 高発現遺伝子を制御する因子をCRISPRスクリーニングし、ANKRD11を同定。ANKRD11は高転写領域で凝縮体を形成し、RNA Pol IIの転写伸長因子を隔離することで過剰な転写を抑えていることを発見 www.cell.com/cell/fulltex...

Epigenome Technologies

epigenometech.bsky.social

30 July 2026 13:03

Epigenetics Update - Condensates of the chromatin regulator ANKRD11 restrict hypertranscribed genes to safeguard development u.epigenome.us/XHlUqkVP Tao Zhang / assumeassume.bsky.social & Nian Liu in Cell #Epigenetics #Condensates #Chromatin #ANKRD11 --- Gain deeper insights at epigenometech.com

Epigenome Technologies

epigenometech.bsky.social

27 July 2026 11:09

Paired-Tag in the Wild! - Single-cell multiomics and chromatin structure reveal gene-regulatory dynamics in heart failure u.epigenome.us/QEV8cqHE @allenywphd.bsky.social, Stavros Drakos, Kyle Gaulton, Bing Ren, & Neil C. Chi in Science #Epigenetics #PairedTag #EpigenomeTech --- epigenometech.com