Al-Sady lab

al-sadylab.bsky.social

13 October 2026 16:12

Took us a bit, but this really special journey is now out, and much improved. Kudos to @agnisrota.bsky.social. It was wonderful to have had to privilege to co-advise you. A showcase of the power of collaboration - a thrill to have worked together on another story with @thebraunlab.bsky.social.

Mir Lab

mirlab.bsky.social

09 October 2026 21:29

1/ Our paper, “Enhancer binding kinetics explain transcription factor hub formation,” is now published! Here we set out to understand why transcription factors form bright clusters or “hubs” in the nucleus, and whether those hubs actually control gene activity. tinyurl.com/38uf8348

Al-Sady lab

al-sadylab.bsky.social

08 October 2026 15:38

This is wonderful news !!!!

Lennart Hilbert

lennarthilbert.bsky.social

08 October 2026 12:32

Expansion protocol developed by and learned from @mpownall.bsky.social Label: indirect immunofluorescence against Nup107 Microscope: @zeiss-microscopy.bsky.social LSM 900 Analysis in Python, visualization with @napari.org Code developed w Claude Science, @anthropic.com 10,000 scientist program

Lennart Hilbert

lennarthilbert.bsky.social

08 October 2026 12:32

Volumetric display of individual nuclear pore locations and intensities in a single cell nucleus (pluripotent zebrafish embryo). The overall embryo was ~16-fold expanded via ChromExM, the display shows a *single* nucleus, though. Experiments, data, and analysis from our @mofrawe.bsky.social