And it works efficiently in different organisms: 🪱🐟🦠 C. elegans, zebrafish, the tunicate O. dioica and the malaria parasite P. falciparum. Study led by Ceron and Acinas labs ar @idibell.bsky.social and @icman-csic.bsky.social #CRISPR #geneediting #genomeediting #Casnucleases 🧵3/4

Show Post

🧬🌊 New preprint from our lab: DO1 Cas9, the first Cas9 nuclease characterised from the deep ocean — recovered from a metagenome at 1,500 m in the Atlantic. ❄️Cold-adapted: it cuts DNA efficiently at low temperature, where mesophilic SpCas9 retains only residual activity. 🧵1/4

Show Post

Lovely meeting old friend (and fellow @princetonupress.bsky.social author) Coleen Murphy @ctmurphy1.bsky.social in Dublin! 😊

Show Post

1/3 Remember our #Magnificent8? 8 mysterious lineages related to animals, known only from environmental DNA. 🧬 We suspected they were just the tip of the iceberg, hiding many more "unknown unknowns". Our new preprint suggests we were right. 🧵 👉https://bit.ly/3TUYowB #protistsOnSky

Show Post

Anyway, we dissect a few paper titles & abstracts, extracting every expectation the authors are raising, explicit and implicit. Then we go to the papers and examine what’s there; how convincing it is; what order it’s presented in (and why); and crucially, what’s missing.

Show Post