The largest dots here are indeed mostly similar motifs (as you can see in the blocks on the diagonal). We have another panel later in the same figure with these connections removed. Most downstream analyses are at the level of "JASPAR homology clusters" to avoid these more obvious effects.

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New genetic variations linked to autism discovered by @utoronto.ca researchers. Their machine learning model identified 100s of previously unknown microexons that appear to play a role in autism. Gene Lay Institute member, #MartinHemberg was part of this work. www.nature.com/articles/s41...

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Congratulations Ben. Fantastic work!

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We’re delighted to report the publication of our new @nature.com paper, ‘A microexon regulatory code reveals autism-linked genetic variation’, a major collaboration with @quaidmorris.bsky.social & additional colleagues, led by co-first authors @geparada.bsky.social & @ha.nnes.io.

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20/ Special thanks to co-first authors Eli Metzner and Karthik Guruvayurappan (@somet3000.bsky.social), plus Kaden Southard (@kmsouthard.bsky.social) and Rico Ardy, for their incredible work, and to co-corresponding author Kushal Dey (@kanishkadey.bsky.social)! www.biorxiv.org/content/10.6...

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