casanovalab.bsky.social
We're a research lab at UT Southwestern Medical Center (TX) and Necker Hospital (Paris) studying human genetic and immunological determinants of infectious diseases. https://www.hgid.org/
👤 Joined on 17 December 2024
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@casanovalab.bsky.socialCheck out these virus-like particles designed by @colinmkim.bsky.social, @casanovalab.bsky.social, and team for studying ligand-receptor interactions. Learn more 👇 and find the plasmids here: www.addgene.org/browse/artic...
Show PostAndrés Soffia, Arturo Borzutzky, and Cristián Sotomayor show that pretransplant immune dysregulation, quantified using IDDA v2.1, predicts overall survival after #HSCT in children with #InbornErrorsOfImmunity. rupress.org/jhi/article/...
Show PostPaul E. Gray, Stuart G. Tangye, and Edwin P. Kirk question the claimed autoimmune disease associations of heterozygous genetic variants in TNIP1 P2RY8 BLK BANK1 and SH2B3, which lack statistical support and where the allele frequency is too high for a Mendelian effect. rupress.org/jhi/article/...
Show PostJAK-inhibitor treatment induces rapid yet incomplete immune reconstitution in #STAT1 gain-of-function. New study from Cecilia Iglesias-Herrero, Rik Schrijvers (KU Leuven) and colleagues: rupress.org/jhi/article/... #InbornErrorsOfImmunity
Show Post@jhumimmunity.org: Delaval et al show that higher serum soluble CD14, a surrogate marker for bacterial translocation & IgA deficiency are independent & early predictive biomarkers for porto-sinusoidal vascular disease risk in patients w/ common variable immunodeficiency rupress.org/jhi/article/...
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