Our AM-3 paper is out in Cell. Opioids are indispensable therapeutics, but have severe side effects. Because they are administered systemically, it is hard to dissect how they work, and to separate side effects. So we built one you can switch on and off with light. 🧵 www.cell.com/cell/abstrac...

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Congratulations to the whole team, and thanks to our collaborators in the Levitz (Weill Cornell), @dirktrauner.bsky.social (UPenn) and Katritch (USC) labs.

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At the end of the day it’s chemistry all the way down

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💯!

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Thank you so much for all of your happy birthday wishes. Honestly, I don’t really feel 100. I feel pretty good. I feel like I’m only 98!

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