reyes-lab.bsky.social
We study DNA replication and genome integrity || live-cell single-molecule microscopy || Bacteria || Budding-yeast || mammalian cells We are at the @biomcgill.bsky.social, @mcgill.ca https://reyes-lamothe.lab.mcgill.ca
👤 Joined on 07 January 2025
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@reyes-lab.bsky.socialSingle-molecule experiments usually test one protein at a time. Our DNA barcodes let us pool many variants, identify every molecule, and measure them all in parallel🔬 Now out in Nature Communications: www.nature.com/articles/s41... @molecularhorizons.bsky.social @espciparispsl.bsky.social
Show PostSuper-excited 🤪 for SPIN-seq! Congrats to Jagadish, Becky, and team! We link the worlds of single-molecule kinetics 🔬 and single-molecule sequencing 🧬 - on the *same* single molecules, surface and instrument! Single-molecule phenotyping + in situ sequencing = SPIN-Seq. www.nature.com/articles/s41...
Show PostmCranberry: A rationally engineered monomeric red fluorescent protein with 85% quantum yield by Premashis Manna and team: www.biorxiv.org/content/10.6...
Show PostWhy is #replication initiation factor Mcm10 essential for replicative helicase activation in yeast but not animals? @labiblab.bsky.social, @yyxia.bsky.social et al now find similar roles for worm & human homologs, masked by partial redundancy with SLD-2/RECQL4 link.springer.com/article/10.1...
Show PostWorking with a great team to organize @keystoneSymposia.bsky.social DNA Replication: Pathway Crosstalk Shaping Physiology and Disease, this April! Join us to explore emerging research in London! keysym.us/KSDNA27 #KSDNA27
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