Our study is out in @cp-immunity.bsky.social: Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse. Grateful to lab members, collaborators, funders, reviewers, @kavithascranton.bsky.social www.cell.com/immunity/ful...

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1/ Why can you encounter an allergen repeatedly before becoming allergic to it? In our new @cp-immunity.bsky.social paper, led by the wonderful Xueping Zhu, we asked whether the sensory neurons that first detect allergens might carry a record of earlier exposures. 🧵 www.cell.com/immunity/ful...

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Check out this cool new paper from Mike Rogers lab @garvaninstitute.bsky.social out in @cp-immunity.bsky.social! Their new model of MKD deficiency (aka Hyper IgD syndrome) as a "prenylopathy": NK cell degranulation defect -> compensatory increase IFN gamma -> autoinflammation. Can Rx with JAKi!

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Resistance of IgG–FcR interactions to shear stress can be engineered, establishing a separate parameter for optimizing antibody effector functions beyond affinity alone. www.cell.com/immunity/pdf... Congratulations to Dr. Bowie Cheng and the whole team 🎉.

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My new comprehensive review of Immune Memory to Vaccines is out! It has an emphasis on human vaccines. It is also accompanied by a full video lecture. Enjoy! @lji.org @cp-immunity.bsky.social authors.elsevier.com/sd/article/S...

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