Siân Owen

Siân Owen

sianowen.bsky.social

Microbiologist & phage phanatic! Enthusiastic explorer of microbial genomes. PI at the Wadsworth Center, New York State Department of Health Asst Prof @albany.edu Currently obsessed with plasmid-dependent phages www.wadsworth.org/research/laboratories/owen

👤 Joined on 03 October 2023

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  • 03 Eki 2023, 19:45
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @sianowen.bsky.social
  • 10 Kas 2023, 02:52
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If you are not familiar with it, PearTree is the replacement for the increasingly creaking FigTree phylogenetic tree viewer. Available as a desktop app and a webapp (which can be embedded in other sites). github.com/artic-networ... for more details. There is even a manual: peartree.live/manual

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A new preprint 🎉 from phagefoundry.org Mycobacteriophages are candidate therapies for drug-resistant mycobacterial infections, but we still don't know how most of them get into their hosts. Our new preprint tackles this challenge 👉🏽 www.biorxiv.org/content/10.6...

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Key findings 🤯 - Determinant usage is largely independent of phage cluster. - Porins (Msp) are candidate primary receptors for 46 phages, the first proposed protein receptor for any mycobacteriophage. - Arabinogalactan is a candidate secondary receptor for 5 phages.

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What does it take for a mycobacteriophage to infect M. smegmatis mc² 155? 🦠🗺️ We mapped it for 70 phages using genome-wide CRISPRi. Our new preprint from the Phage Foundry is out! (phagefoundry.org) 🥳🧵 Read the preprint here: www.biorxiv.org/content/10.6...

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Heads-up! I’ll be starting my research group at MedUni Vienna in January 2027, with postdoc and PhD positions available soon. Looking for people interested in bacteria–phage interactions, bacterial defense systems, and phage anti-defense strategies. Please send your CV: anna.lopatina@univie.ac.at

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