Andrea Ganna

andganna.bsky.social

17 October 2025 09:05

🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much. Our new study in Nature Genetics including 9 disease and 7 biobanks shows: • Susceptibility variants ≠ survival • PRSs for onset weak at predicting progression • Lifespan PRS predicts survival better

Andrea Ganna

andganna.bsky.social

17 October 2025 09:05

💥 New preprint & our first RCT! 💥 Does an extremely high or low BMI polygenic score influence weight loss after a diet intervention? GENEROOS is a 6-month randomized diet vs. control trial testing if genetic predisposition to higher BMI affects weight loss in overweight adults

Andrea Ganna

andganna.bsky.social

17 October 2025 09:05

🎉 New preprint out! "Removing genetic effects on plasma proteins enhances their utility as disease biomarkers" We show that adjusting plasma proteins for genetic effects can make them stronger predictors of disease 👉 doi.org/10.1101/2025...

Andrea Ganna

andganna.bsky.social

24 May 2025 09:55

Our team presentations at #eshg25 #eshg2025. looking forward!!

Daniela Fusco

danifusco.bsky.social

12 April 2025 13:16

Finally out!🤩 My first first-author publication is now online. We explored the molecular mechanism underlying the genetic correlation between #BMI and #brain morphology. @cbuunito.bsky.social journals.plos.org/plosgenetics... I want to sincerely thank all the co-authors: