institutimagine.bsky.social
🔬 Premier centre européen dédié aux maladies génétiques. 📍 Campus Necker - Enfants Malades, Paris | #Recherche #Santé #Innovation 🌐 www.institutimagine.org
👤 Joined on 16 December 2024
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@institutimagine.bsky.socialA fantastic collaborative effort with Tsuyoshi Osawa and many others! 🙏 Huge credit to Mayuko Segawa and Sho Aki for leading this study!! And a massive thanks to everyone involved!! 🔥 @mrc-mbu.bsky.social @institutimagine.bsky.social
Show PostDelighted to share our lab’s latest paper, published in @science.org , uncovering a new role for Golgi-derived vesicles and phosphoinositides regulating mitochondrial fusion! 👇 www.science.org/doi/10.1126/...
Show Post8/8 Huge credit to first author @cakirumut.bsky.social for driving this work, and to @mfederica.bsky.social and @souad-youjilabadi.bsky.social from #RETROGEN Lab @inem-necker.bsky.social @institutimagine.bsky.social @cnrs.fr & our collaborators at UCLA and MPI. Preprint: doi.org/10.64898/202...
Show Post7/8 Together, the atlas maps where a pro-neurogenic signal reshapes chromatin and points to TE-derived sequences as possible parts of the regulatory network. We hope this cell-type-resolved resource helps others explore the adult hippocampus.
Show Post6/8 Several TE families were bound by neurogenic transcription factors. Their nearby genes are linked to neuronal differentiation and synapse formation. We propose these TE-derived sequences as candidate regulatory elements—not yet proven causal switches.
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