g-heller.bsky.social
Drugging intrinsically disordered proteins Co-Founder/CEO/CSO, Bind Research (https://bindresearch.org/, @bindresearch.org) PI, eXtreme Dynamics & Therapeutics Lab, UCL (she/her)
👤 Joined on 01 October 2023
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@g-heller.bsky.socialFor the remaining signals, it returned a ranked shortlist of likely candidates, with the correct residue appearing on that shortlist more than 97% of the time.
Show PostAssigning the backbone of a disordered protein is often weeks of work before the biology can even start. I’m sure I’m not alone in having spent long days staring at a stack of spectra, wishing for a just a little more resolution. We built SpinForecast to help!
Show PostWant more? Try the tool yourself: tools.bindresearch.org/bindbox/SpinForecast You can play with the underlying NMR data here: tools.bindresearch.org/bindbox/BMRB_Chemical_Shifts Check out the source code: github.com/bindresearch/BindBox
Show PostFellow disordered protein 🍝 and NMR nerds 🧲: check out the preprint: www.biorxiv.org/content/10.6...
Show PostNew to #NMR? Our blog post explains the science behind SpinForecast and why assignment matters: bindresearch.org/news/solving... #NMRchat #ChemSky
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