the-asci.org
The ASCI is a nonprofit honor society of physician-scientists. Founded in 1908, the Society is home to 3,500+ members across academic medicine and industry. https://the-asci.org Take action for federal funding of research: https://www.fundresearch.org/
👤 Joined on 19 November 2023
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@the-asci.bsky.social@the-asci.bsky.social → @the-asci.orgSuggesting a novel therapy for systemic sclerosis: doi.org/10.1172/jci.... @eduardomarban.bsky.social & team report that an orally delivered noncoding RNA (TY1) reduces inflammation and organ fibrosis in models of systemic sclerosis through inhibition of the cGAS/STING axis. @the-asci.org
Show PostSaturday Special💫: Welcome to the kidney! R Ariel Gomez & team examine the role of renin cells in renal neurovascular morphogenesis & remodeling. The video: mouse kidney cortex with renin cells (magenta), the renal arterial tree (green), nerve fibers (yellow): doi.org/10.1172/jci.... @the-asci.org
Show PostProposing a combination treatment for reducing death from cerebral malaria: doi.org/10.1172/JCI2... Alvin H. Schmaier & team report on a role for bradykinin in cerebral malaria and find plasma kallkrein inhibitors target host-mediated vascular dysfunction. @the-asci.org
Show PostChanging the paradigm for loss of the Y chromosome: doi.org/10.1172/jci.... Dan Theodorescu & team report Y chromosome loss increases progressively from healthy tissues to cancer, suggesting it is an early and previously unrecognized driver of cancer development. @the-asci.org
Show PostAlpha-Gal syndrome is a tick bite-associated allergy characterized by reactions to alpha-Gal found in red meat doi.org/10.1172/JCI1... Peter D. Crompton & team show the potential of alpha-Gal-specific mAbs to prevent the allergy by blocking IgE binding to alpha-Gal. @the-asci.org
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