Tatiana Dimitriu
tatianadimitriu.bsky.social
@royalsociety University Research Fellow in St Andrews. Bacterial evolution, mobile genetic elements & defence systems, antibiotic resistance, social interactions. 🇫🇷 with some 🇷🇴 and 🇺🇦 roots. She/her
👤 Joined on 31 October 2023
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- 31 Eki 2023, 11:13
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@tatianadimitriu.bsky.social - 10 Kas 2023, 02:55
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Do you like riddles(and molecular biology)? Maybe you can help me solve this one. We’ve found a short piece of DNA (a plasmid) present in almost all plague samples from the Second Plague Pandemic (1338-1840), but absent in all earlier or later plague cases. www.biorxiv.org/content/10.6...
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Good job we don't expect more global pandemics and more historically "tropical" diseases to spread to the UK with climate change.
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you're certainly aware that the leading region of conjugative plasmids is not only optimized for translation but also for transcription. and their replication is driven by this transcription.
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Thanks to @zerdos.bsky.social who led this work. He worked tirelessly in and out of the lab. It is also the first paper out of my group which is a nice win. Shout out to @tatianadimitriu.bsky.social for advising on plasmid transfer assays, and Profs Buckling and Raymond who aren't on here.
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