casperberger.bsky.social
Cryo-ET & (plasma) FIB lamella milling. Senior Application Expert @ The Rosalind Franklin Institute
👤 Joined on 04 February 2025
Followers
Following
Total Posts
@casperberger.bsky.socialPS: These are my own, personal opinions, not the ones of my employer. I express them because I care deeply about how science is done and I am worried the UK is turning into the wrong direction.
Show Post1/5 Cryo-EM gives high-resolution RNA structures, but only when high Mg²⁺ freezes out their motion. At physiological conditions, RNAs are dynamic and 3D reconstruction fails. Can we still learn their folding equilibria? New preprint: yes, straight from the raw particle images👇
Show Post🎥 Recordings from the recent Wellcome-MRC In Situ Cryo-ET Course 2026 are now available on YouTube! From sample preparation and cryo-FIB milling to data collection, image processing and STA, check it out here: www.youtube.com/playlist?lis... #CryoET #CryoEM #StructuralBiology #eBIC #Microscopy
Show PostEvery cell has an organelle signature — a “fingerprint” created from the shape, size, & arrangement of its internal structures. Scientists at our Janelia Research Campus can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹 Feliciano Lab@
Show PostOut today in @nature.com: our review on how single cells evolve into multicellular organisms. With Ozan Bozdag, @kaitong25.bsky.social, Peter Yunker, and @matthewherron.bsky.social. rdcu.be/9ZuiKow9twKa For an overview, check out the video below.
Show Post