evasileva.bsky.social
Research Faculty, Center for Cancer and Immunology Research at Children’s National Hospital in Washington, DC. Using #zebrafish 🐟 to learn more about pediatric cancer #VasilevaLab
👤 Joined on 13 December 2024
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@evasileva.bsky.socialThe Vasileva Laboratory at @childrensnational.bsky.social, led by @evasileva.bsky.social, explores the developmental origins of childhood cancer, focusing on the molecular and cellular mechanisms that drive tumor initiation and progression.
Show PostJuly is Sarcoma Awareness Month 🎗️ With the help of the tiny but mighty zebrafish, researchers are expanding what we know about these aggressive cancers 🐟👩🔬 Learn more about the research that is making tank-to-bedside impacts on patients ⬇️ 1/3 #KnowYourZDM #zebrafish #ZDMS #sarcoma #DiseaseModels
Show PostOur second example was led by @kendalllab.bsky.social in @amatrudalab.bsky.social. They used human PAX3-FOXO1 fusion genes to drive tumors in zebrafish. Using these transgenic fish, they identified HES3 as a mediator of rhabdomyosarcoma tumorigenesis. It is now a biomarker for aggressive tumors. 3/3
Show PostOur first example was led by @evasileva.bsky.social in @amatrudalab.bsky.social. Their research determined the origin of Ewing Sarcoma to be reprogrammed neural crest cells that become mesoderm and drive aggressive tumors. This discovery identifies a potential therapeutic target for physicians. 2/3
Show PostFantastic! Highly recommended for anyone looking to do great science with a brilliant and wonderful mentor!
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