Elena Vasileva

Elena Vasileva

evasileva.bsky.social

Research Faculty, Center for Cancer and Immunology Research at Children’s National Hospital in Washington, DC. Using #zebrafish 🐟 to learn more about pediatric cancer #VasilevaLab

👤 Joined on 13 December 2024

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  • 13 Ara 2024, 21:47
    🎉 Bluesky'e katıldı - İlk kullanıcı adı: @evasileva.bsky.social

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The Vasileva Laboratory at @childrensnational.bsky.social, led by @evasileva.bsky.social, explores the developmental origins of childhood cancer, focusing on the molecular and cellular mechanisms that drive tumor initiation and progression.

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July is Sarcoma Awareness Month 🎗️ With the help of the tiny but mighty zebrafish, researchers are expanding what we know about these aggressive cancers 🐟👩‍🔬 Learn more about the research that is making tank-to-bedside impacts on patients ⬇️ 1/3 #KnowYourZDM #zebrafish #ZDMS #sarcoma #DiseaseModels

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Our second example was led by @kendalllab.bsky.social in @amatrudalab.bsky.social. They used human PAX3-FOXO1 fusion genes to drive tumors in zebrafish. Using these transgenic fish, they identified HES3 as a mediator of rhabdomyosarcoma tumorigenesis. It is now a biomarker for aggressive tumors. 3/3

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Our first example was led by @evasileva.bsky.social in @amatrudalab.bsky.social. Their research determined the origin of Ewing Sarcoma to be reprogrammed neural crest cells that become mesoderm and drive aggressive tumors. This discovery identifies a potential therapeutic target for physicians. 2/3

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Fantastic! Highly recommended for anyone looking to do great science with a brilliant and wonderful mentor!

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