Douglas W. Houston
dhouston.bsky.social
Developmental Biologist. Professor, #UIowa Director, Developmental Studies Hybridoma Bank, @dshb-antibodies.bsky.social Views my own
👤 Joined on 31 December 2023
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- 31 Ara 2023, 16:57
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dshb.biology.uiowa.edu We should support and make better use of hybridoma bank Maintained by a small team at the University of Iowa’s Developmental Studies Hybridoma Bank
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A massive update: At least ~15 companies~ are selling scientists antibodies using faked validation data. We've documented 18,000+ manipulated images on 17,000+ products sold by leading laboratory suppliers including Thermo Fisher, Abcam, Santa Cruz Biotechnology, Millipore Sigma and Bio-Techne. 1/🧵
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Cross-species reactivity isn’t guaranteed. Before ordering, check sequence conservation with BLAST, inspect structural context near an epitope, and search the literature for prior use. What else is on your checklist?https://dshb.biology.uiowa.edu/blog#post=choosing-an-antibody-with-confidence
Show PostSpotted in @braincomms.bsky.social! Researchers from #CHEO Research Institute, among others, used 4 of DSHB's anti-MHC mAbs to examine how different genetic forms of CMS respond to a MuSK‑targeting antibody.
Show Post🔎 Spotted in @jci.org! Researchers at the University of Osaka, among others, used our anti-MHC [MF20] antibody to identify an SGCB splice-site mutation linked to dilated cardiomyopathy. 📄 tinyurl.com/2hdyfkys 🧫 dshb.biology.uiowa.edu/MF-20
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