jk-swietek.bsky.social
Gabilan Assistant Professor of Molecular and Cellular Biosciences & Quantitative and Computational Biology @ USC Prior @EPFL & @Columbia University #GeneRegulation #NonCodingMechanisms #TranscriptionFactors
👤 Joined on 08 August 2024
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@jk-swietek.bsky.socialIMO the paper of the year in the gene regulation field - such a clean and clear study, showing how promoter-enhancer contacts mediate transcriptional activation. www.cell.com/cell/abstrac...
Show PostNew commentary from the lab - can we identify principles of transcriptional regulation & cis-regulatory element (CRE) control of gene expression? With @jcornwallscoones.bsky.social & @joadelas.bsky.social in @cp-molcell.bsky.social A thread 🧵 doi.org/10.1016/j.mo...
Show PostOur AM-3 paper is out in Cell. Opioids are indispensable therapeutics, but have severe side effects. Because they are administered systemically, it is hard to dissect how they work, and to separate side effects. So we built one you can switch on and off with light. 🧵 www.cell.com/cell/abstrac...
Show Post1/ Our paper, “Enhancer binding kinetics explain transcription factor hub formation,” is now published! Here we set out to understand why transcription factors form bright clusters or “hubs” in the nucleus, and whether those hubs actually control gene activity. tinyurl.com/38uf8348
Show PostThe craziest compound-impurity story I’ve ever heard:
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