robertife.bsky.social
https://www.helmholtz-munich.de/en/ife
👤 Joined on 21 November 2024
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@robertife.bsky.socialmRNA processing links to tumorigenesis: @agatakstepien.bsky.social , Deepshika Pulimamidi, @stoplab.bsky.social show shortened cleavage-to-termination distances in colorectal cancer cells, correlating with increased gene expression & dependence on CPSF73 and PCF11 link.springer.com/article/10.1...
Show PostWe often say cancers reactivate embryonic programs, but how often does this happen? and is it always bad? In this study, we develop EmbryoRadar to detect widespread expression of preimplantation transcriptional programs across all cancers, with varied patient outcomes www.biorxiv.org/content/10.6...
Show PostNew commentary from the lab - can we identify principles of transcriptional regulation & cis-regulatory element (CRE) control of gene expression? With @jcornwallscoones.bsky.social & @joadelas.bsky.social in @cp-molcell.bsky.social A thread 🧵 doi.org/10.1016/j.mo...
Show PostSee below for a cancer biology-oriented view on our new paper by co-first author & bioinformatician Deepshika Pulimamidi 👇
Show PostImportant work on H4K16 acetylation
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