Science Magazine

science.org

12 February 2026 13:03

A new Review discusses the immune makeup within the peritoneal, pleural, and pericardial cavities, including changes that occur during conditions such as cancer and endometriosis. Learn more in #ScienceImmunology: https://scim.ag/4aeAAYr

Seth Thomas Scanlon

immunoeditor.bsky.social

22 September 2025 11:14

Now in #Science #Immunology, @drtesutherland.bsky.social & al report chitinase-like proteins (CLPs) make distinct contributions to airway pathology independent of #IL13- & #IL17 –mediated signaling in 🐀 #asthna model! CLPs orchestrate airway #ECM remodeling, & can be both protective & detrimental!

Tara Sutherland

drtesutherland.bsky.social

22 September 2025 11:10

Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...

Tara Sutherland

drtesutherland.bsky.social

22 September 2025 11:10

Surprisingly, airway ECM remodelling was protective for lung function, and rather seems to support epithelial function. Huge amount of work by @james-ep.bsky.social @hetompkins.bsky.social and a tremendous amount of help and support from all of our collaborators at Aberdeen and Manchester

Tara Sutherland

drtesutherland.bsky.social

19 September 2025 19:26

If you like the lung, immune cells, tissue cells, ECM and imaging check it out! Huge effort from everyone involved both collaborators and the lab, especially @james-ep.bsky.social who worked tirelessly on analysing this complex dataset, and putting everything together in a great paper.